Beyond Blood Pressure
نویسندگان
چکیده
منابع مشابه
Clinical perspective Outcome beyond blood pressure control?
The last two decades witnessed the publication of a large number of clinical outcome trials of blood pressure lowering agents in hypertensive patients or normotensive subjects with a high cardiovascular risk profile. Placebo-controlled trials of antihypertensive drug treatment in middle-aged or older hypertensive patients predominantly with diastolic hypertension proved that a 5–6 mmHg decline ...
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متن کاملHypertension, angiotensin, and stroke: beyond blood pressure.
Hypertension (HTN) is a major risk factor for all stroke subtypes, infarction as well as hemorrhage.1,2 Evidence from clinical trials shows that control of blood pressure (BP) leads to a substantially lower risk of stroke.3 HTN exerts detrimental actions on the cerebral circulation that play a critical role in its ability to promote cerebrovascular diseases. Angiotensin II (Ang II) is a key med...
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Aldosterone was in the past considered only as a prohypertensinogenic agent. It has recently become clear that apart from the classical endocrine action, i.e. causing blood pressure elevation as a result of salt retention, aldosterone has numerous blood-pressure-independent actions on nonepithelial tissue. Under conditions of high salt concentration, aldosterone is injurious to the kidney, hear...
متن کاملBeyond blood pressure: subtle effects of drug classes.
In this issue of Arteriosclerosis, Thrombosis, and Vascular Biology, Schillaci et al1 raise an interesting possibility—that a drug class (protease inhibitors) can have subtle arterial ill effects, which are not apparent from conventional blood pressure recordings. The authors provide evidence of aortic stiffening (measured as carotid–femoral pulse wave velocity [PWV]), increase in wave reflecti...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2005
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000189321.13314.f7